Histopathologic Findings of Eyes Enucleated After Treatment with Chemosurgery for Retinoblastoma

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Histopathologic Findings of Eyes Enucleated After Treatment with Chemosurgery for Retinoblastoma

INTRODUCTION Intra-arterial chemotherapy (chemosurgery) for the treatment of retinoblastoma has been performed more than 1600 times (more than 1400 times in Japan and 200 times in New York) over the past 20 years.Despite this treatment's success some eyes cannot be saved and require enucleation. Here we report the histopathologic findings of the remaining intraocular tumor of eyes that were enu...

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Histopathologic findings in eyes with retinoblastoma treated only with chemoreduction.

OBJECTIVE To evaluate the histopathologic findings in the eyes with retinoblastoma that had been treated only with chemoreduction. DESIGN Clinicopathologic series. Study Material Ten eyes of 8 patients with retinoblastoma that were enucleated after therapy consisting only of systemic chemotherapy (chemoreduction). METHODS All cases received a chemoreduction regimen including a combination o...

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Enucleated eyes after failed intra-arterial infusion of chemotherapy for unilateral retinoblastoma: histopathologic evaluation of vitreous seeding

Selective intra-arterial chemotherapy (IAC) has been adopted by many ocular oncology centers to treat advanced intraocular retinoblastoma. In this report, we describe two patients with unilateral intraocular retinoblastoma and persistent vitreous seeding, who were treated with IAC after failed systemic chemotherapy. Despite multiple sessions and increasing dosage of drug delivery, vitreous seed...

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"etiologies of pseudoretinoblastomas in histopathologic speciemens of enucleated or exenterated eyes with clinical diagnosis of retinoblastoma "

retinoblastoma is the most common primary intraocular malignancy in childhood. enucleation remains the treatment of choice in many children because the eye can not be salvaged with any other treatment modality. in some cases after enucleation etiologies other than retinoblastoma are detected in histopathologic review (pseudoretinoblastomas). this study aims to evaluate the prevalence and etiolo...

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histopathologic risk factors of retinoblastoma: a retrospective study of 104 enucleated eyes

purpose : to introduce a novel classification system for the extent of choroid invasion and to analyze the incidence of histopathologic risk factors (hrfs) in the patients with retinoblastoma in china methods : the clinical data of 104 enucleated eyes diagnosed with retinoblastoma were retrospectively reviewed, and the pathological re-examination of the enucleated eyes was conducted. results : ...

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ژورنال

عنوان ژورنال: The Open Ophthalmology Journal

سال: 2011

ISSN: 1874-3641

DOI: 10.2174/1874364101105010001